pandemic tracking contagions from cholera to ebola and beyond

Additionally, that cholera today is largely a problem for countries without modern sanitation may create false assurances about all countries’ risks for pandemics. While some dimensions of cholera can be stretched to fit aspects of recent epidemics, there is scant evidence supporting how the central thesis of the cholera paradigm, that transmission can be in part explained by climate, applies to pandemics caused by other organisms, such as influenza.

The book’s central metaphor, the cholera paradigm, although somewhat instructive, is an imperfect model for explaining the rise and spread of pandemics. Scientists and practitioners who have been grappling with these diseases may quibble with Shah’s simplified explanations. Shah’s personal experience in battling methicillin-resistant Staphylococcus aureus within her family serves as a particularly compelling illustration of how challenging even seemingly simple infections can be. In doing so, Shah offers useful accounting of the history of the most consequential epidemic events that have occurred in the past 50 years. While tracking cholera’s journey, Shah discusses other pathogens that have emerged and progressed down cholera’s path from isolated microorganism to pandemic pathogen: severe acute respiratory syndrome, Ebola, Middle East respiratory syndrome, West Nile, and Lyme disease, as well as pathogens that have acquired antimicrobial resistance.

In doing so, Pandemic takes its reader from the initial “spillover” of cholera from copepods in the Sundarbans wetlands of the Bay of Bengal through a series of historical outbreaks, including the recent outbreaks in Haiti. Although there have been several other books that have examined the origins of pandemics, Shah attempts to differentiate her analysis by using Rita Colwell’s description of the “Cholera Paradigm” as a framework for discussing the categories of social and environmental change for example, locomotion, filth, crowds, and social dynamics that can explain how the microbes can emerge and spread disease around the world ( 1). Given these events, Pandemic: Tracking Contagions, From Cholera to Ebola and Beyond by Sonia Shah makes for a very timely read. As we struggle to understand both the scale and impact of the Zika and Ebola crises, we are forced to once again ask: how did this happen and what can we do to prevent the next one?

Both viruses, previously thought to cause only limited outbreaks, surprised the people of the world with a seemingly sudden ability to spread across multiple countries and cause illness in new, previously unthinkable ways.

During the past 2 years, back-to-back epidemics of Ebola and Zika have stunned even seasoned public health officials with unprecedented levels of illness and death that have been associated with these events.

Pandemic tracking contagions from cholera to ebola and beyond